Maybe someone can help me out with this… Every time I look at the scientific literature, it suggests that there is likely a link between acetaminophen use and changes in neural development in fetuses/very young children. Folks on Lemmy seem to feel that there is in fact NO evidence. Am I just looking at the wrong papers?
For example: https://pmc.ncbi.nlm.nih.gov/articles/PMC10814214/ https://www.sciencedirect.com/science/article/pii/S0892036224000011 https://academic.oup.com/toxsci/article-abstract/138/1/139/1672900 https://www.frontiersin.org/journals/toxicology/articles/10.3389/ftox.2022.867748/full
There’s a correlation, but not a causal link.
For example, lets say… A certain virus, that has a fever and headache as a symptom. If a pregnant woman contracts said virus, she likely will take acetaminophen for it.
Now, let’s also say, that particular virus can cause the markers responsible for autism to activate.
So, since the virus is unknown, the only correlation we see is the acetaminophen use, while pregnant.
Did the unknown (yet) virus cause it, or did the acetaminophen use cause it?
This is a study in mice, using the word “likely” here is a stretch. And the discussion is specifically about links to autism, not developmental problems generally.
“No conclusive evidence” -> “No evidence.”
“Conclusive” here is used as a weasel word.
Wait, 500mg Tylenol is “extra strength”? Dafalgan Forte is 1g.
Is Tylenol suing the living christ out of this administration or what? Where are they at in all of this? Not least of which, they should be saying acetomenophen/paracetamol, rather than the brand name of one manufacturer of those drugs
Honestly if Tylenol is smart they’ll wait for the administration to get it out of their system and then bring the lawsuit, maximize the amount of dumbfuck statements so as to make the case as strong as possible.
I just want to know what Tylenol did to piss off Trump & friends
They didn’t. Crackhead Kennedy just needs a scapegoat and that’s the correlation during that time period. Trumps making America weaker but himself stronger
To be fair I don’t think CONCLUSIVE evidence is the bar we need to pass to be careful.
AFAIK paracetamol is proven to be very safe when used as recommended.
Also AFAIK there is ZERO evidence it should cause autism.
This is the vaccine bullshit all over again, false claims of crazy side-effects without any evidence, but only anecdotal bullshit, that if true research would have detected decades ago.
It’s like claiming water causes traffic accidents: “Hey my son drank a cup of water, and the next day he died in a traffic accident!”
Damned it’s tiresome to have to hear and see those morons get so much space in media by other morons all the time.I’m not blaming this article, that’s an OK article, but the reason this article exist is the above.
That is the problem. The language of science versus the understanding of the language is science by the wilfully ignorant and shockingly stupid.
“There’s is no conclusive evidence…”
“So there is evidence!”
The most extensive study of acetaminophen use by pregnant women following 2.4 million women showed NO EVIDENCE OF ANY LINK BETWEEN TYLENOL/PARACETAMOL USE AND AUTISM.
The science/medical community needs to dumb it down the dumbth.
It’s pretty stupid to call it conclusive evidence, since evidence in science very rarely is conclusive. In medicine it’s generally statistic, and there are always a chance if you test 5 million people, that the 5 million and 1 will be different.
So it’s not about average people being unable to understand scientific terms in this case, but it’s simply not a reasonable statement by any normal use of the language. Of course there isn’t conclusive evidence, because that’s an insane bar.
If this shit caused autism then a stupid massive amount of gen Z and gen A would be autistic… which they aren’t…
It’s so embarrassing that other countries even need to address the antiscience dumbfuckery coming from this administration.
American propaganda easily infects the anglophones here sadly.
Not just the anglosphere, there was also a news story debunking the link here in Norway
And here in colombia.
Have you considered not having those?
I feel like that’s most of you. Both sides—I mean, fact that two sides even exist is enough—just kind of sit around waiting to be told what to think by your feeds.
I’ve called people out on here for peddling bullshit, “Well the right do it and we won’t win by being nice.”
WHAT?!
Meanwhile a bunch of users nomnomnomming up the content.
It’s such a weird country.
Kind of why you only see stuff on Lemmy that supports a specific view and bias and never challenges it. This is a place for circlejerking, not some common ground of diverse political views and interests. We only post content here that brings release, ensuring
Edit: Oh go on then, change my mind. At least where I’m from—any developed nation in the world you can think of—I can say that without worrying about someone from my “tribe” shooting me in the neck.
But what about Paracetemol?
/s - its the same thing, and absolutely motherfuck the American pharmaceutical industry for giving it another name and confusing everyone.
Paracetamol is safe. It’s that acetaminophen that you have to avoid! /s
Paracetamol, in large and long-term doses, is proven to cause liver damage.
It just doesn’t have a fucking thing to do with autism.
Had to Google because I’ve wondered why but never actually looked into it, and so in case anyone else also hasn’t:
Charles Frédéric Gerhardt (1852): This French chemist is sometimes credited with being the first to synthesize the compound, though this is debated.
Harmon Northrop Morse (1878): Morse, an American chemist, is also cited for first preparing the compound. However, the discovery was not pursued for medicinal purposes at the time.
I haven’t gone further than that because I’m going to be late to work, really pushing the limit today, but something I’m definitely interested in looking into.
Regardless, the drug name is N-acetyl-para-aminophenol, and so both Names™ are in there. Stupid! Although paracetamol is kinda stretching it.
Let’s just call it N-tylol. Jesus that’s how they came up with Tylenol.
Paracetamol is the correct generic name in English outside of north America, and is broadly used throughout Europe/middle east and Africa as the generic name.
Acetaminophen is the generic name largely only in north america
I got that part. It was mainly the why.
Japan apparently uses acetaminophen.
America is the only country that allows direct to consumer drug marketing.
Not true.
And New Zealand
You know what is though? Air pollution.
There’s never been any evidence of anything singularly, conclusively being linked to autism, which is what’s left so much room open for conspiratory nutcases and bored housewives to “do their own research” and come up with their own fantastic fairy magic stories.
It wouldn’t matter WHAT the administration said, people are going to believe what they’re going to believe.
What’s funny though, is the fact that RFK and Trump didn’t explicitly call out vaccines, the go-to anti-science grift everyone is using, made a lot of people on the right really mad. It should make for a clear indicator that the whole thing is a scam and a grift, but unfortunately conservative minds don’t work that way, and it will just make the vaccine-fearful even more fearful.
Being really good at trains has been conclusively linked to autism.
Rfk was trying to say Trump should get the peace prize for the covid vaccine.
So, despite all of their vax bashing, I think he’s still cooking that scheme and don’t want to pin autism on it right now.
oh, that explains it! I was wondering why the sudden shift in scapegoat
If they had tried to link autism to vaccines, they would have had to show some evidence to support it. They do not have any evidence to support the claim that vaccines cause autism.
But there isn’t evidence linking autism to Tylenol either, right?
There is a correlation between mothers who take tylenol while pregnant and children who develop autism in some studies.
But it could be just as likely that autism is both hereditary and comorbid with other painful diseases like Ehlers-Danlos syndrome, mom is also autistic but from a generation that doesn’t get diagnosed, and she’s also in pain and taking tylenol, and her kid gets autism because of genetics and not tylenol.
There is a correlation between mothers who take tylenol while pregnant and children who develop autism in some studies.
All people with autism, also had mothers who consumed water during their pregnancy… Did water cause autism?
But it could be just as likely that autism is both hereditary
At this point, it’s almost a certainty that this is the case, possibly activated by environmental influences during pregnancy. However, none of the influences have been identified, as there’s (Last I looked) about 30 separate DNA sequences that are related to autism in people.
For what it’s worth… there’s about the same number of DNA sequences involved in someone requiring corrective lenses.
There’s also a correlation between mothers who breathe air while pregnant and children who develop autism. And sometimes even children who don’t!
That was shit, underpowered science that should never have been funded or published. A proper Swedish study of 2.5 million proves, without a doubt, no correlation.
Granting agencies and universities need to get their shit together and teach epidemiologists how to do proper science because at this point, it’s pretty close to psychology.
An article from last April in JAMA also compared between a no-control cohort and a sibling-control cohort. When a control is there for comparison, the potential correlation goes away meaning it’s just as likely any findings are confounded anyway.
Oh look, bullshit information without a source. Also correlation is not the same as causation. Hopefully this snippet is short enough for you to ingest:
https://www.nature.com/articles/d41586-025-02876-1
The study led by Ahlqvist harnessed data from nearly 2.5 million children born in Sweden between 1995 and 2019 and — from the country’s extensive health records — data on acetaminophen prescriptions during pregnancy and on self-reported use collected by midwives, as well as whether children later received autism diagnoses.
The study showed that around 1.42% of children exposed to acetaminophen during pregnancy were autistic, compared with 1.33% of children who were not exposed ─ a “very small” difference, says Ahlqvist.
The team also compared pairs of siblings (born to the same person), in which one had been exposed to acetaminophen and one had not. Siblings share half of their genome, a similar upbringing and maternal health, so differences in autism are more likely to be due to the drug. Using this method, the researchers found no association between acetaminophen and autism — which supports the idea that links found in other studies could be explained by confounding factors.
A large, high-quality study from Japan of more than 200,000 children — also using sibling comparisons and published this year — found no link between acetaminophen use in pregnancy and autism.
No but gimme five minutes in excel and I could get you some.
It might take then 50.
Behind closed doors, they probably are beginning to understand that it would be a public health disaster if they actually removed access to vaccines so Tylenol is a more innocuous scapegoat. I always avoided it because problems with alcohol interaction. In reality the culprit is more likely to be heavy pesticide use enabled by gmo roundup resistant crops.
Pretty sure several Greek philosophers were autistic. It’s obvious from their writings. Tylenol didn’t exist then, so what’s the excuse there?
Oh wow, jeez, maybe neurodivergence has always existed. No, it can’t be that. Also, we just have to make sure everyone conforms because other people being ‘weird’ makes us uncomfortable.
You mean autistic people…are human? 🤯
Imagine thinking neurotypes are binary and not a gradient of human experiences. Imagine also thinking one swath of neurotypes is a disease and not also simply part of said human experience.
These are also the same jackasses who think only one sleep pattern is “correct” despite…well, history, but that’s a separate rant.
No actually autistic people think “in black and white” and I’m not autistic so I do not think “in black and white.” I am very smart and correct (and good at logic)
The stoics : 😐
Many countries avoid acetaminophen for good medical reasons related to liver damage. But no way will a xenophobic country take lessons from another country.
We somehow need to convince these people that any and all medical treatment will give you autism or turn you trans or something.
Did you know that if you get a blood transfusion and the donor is trans, you’re exposed to enough hormones that you can become trans too? It’s way too dangerous to get a blood transfusion these days. /s
(Using this as an example specifically because I know trans people who were turned away from giving blood in the first place, including a trans girl I used to date. She was assumed to have a significantly more risky sexual history than she actually did, and I’m also negative for HIV)
While the effort is appreciated. This news came from a failed gameshow host who ran 2 different casinos into the ground and a lean addict who swims in sewage for fun. 2nd guy also has a worm in his brain.
Like i said. Appreciated, but unnecessary. The people who believe those two are the same people who were shitting out their intestinal lining a few years ago to “own the libs” while they died in droves because vaccines are the mark of Satan or something.
I’m so sick of this misinformation circulating about RFK having a worm in his brain. He had a worm in his brain. It died because RFK’s thoughts are that toxic.
Fake news. He is the worm now.
It’s why he talks like that.
In seriousness, he likely talks like that due to vocal chord paralysis caused by heroin.
Or… going back to he is the worm now… Just a worm in an Edgarsuit… Or, in this case… a Robertsuit.
Right. Even his own body wants him to shut up.
“Canada confirms it WAS the vaccines all along!”
found funny the antivaxx community got offended with Trump for the baseless Tylenol claims
Again the problem is how this is written … “no conclusive evidence” will be read as “There is a small sliver of evidence pointing towards the general direction of…”
It should say “There is no evidence of… at all”.
… but that isn’t true, which is the very reason for why they phrase it like that. The Trump administration didn’t invent the “paracetamol -> autism” hypothesis. There’s been papers published on it for years.
The state of the science is that there’s correlation, but not causation. Unfortunately the difference between those two things is a bit difficult to communicate to the general public.
Exactly this… I’m so tired of shoddy “journalism”.
